Due to persistent anxiety after 6–8 weeks, escitalopram was increased to 10 mg daily, and clonazepam to 0.25–0.5 mg nocte as needed. After 2 weeks of nausea, elevated anxiety and insomnia, citalopram was discontinued, and escitalopram 5 mg daily commenced with clonazepam 0.25 mg nocte. R, a 78-year-old man with no prior psychiatric history, was treated for depression with citalopram 10 mg daily after 4 months of treatment for Waldenström macroglobulinemia.
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